Olly is a gay teen with disability who discovers that his two straight best friends are dating each other. Frustrated by his body, he chooses to undertake a pioneering medical procedure: a transplant that puts his mind into the body of a beautiful young able-bodied woman. When his friends see through the beautiful, blo…

一场没有人道底线的医疗试验，一群没有未来的死刑囚犯，这一切都在渺无人烟的北大西洋孤岛监狱中发生。当权力吞噬了人性，这场神秘试验失去控制，人类创造了令自己都不敢想像的病毒。整个岛屿瞬间成为一座可怕、充斥着感染者的绝望炼狱，到底谁还能活到最后？

供职于某旅游杂志的记者皮特麦克卡尔（Michael Vartan 饰）参加了一个在澳大利亚卡卡度国家公园举行的水上冒险旅行团。不过这次旅程对寻求刺激的人们来说似乎过于枯燥，美丽的女导游凯特瑞恩（Radha Mitchell 饰）带领大家进入尚未开发的水域。正当游客们享受这令人惊叹的湖光山色之时，不远处的天空升起了求救的信号弹。凯特不顾大家返回的要求…